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Anticoagulants: Phenobarbital lowers the plasma levels of dicumarol (identify Formerly employed: bishydroxycoumarin) and triggers a lower in anticoagulant action as measured via the prothrombin time. Barbiturates can induce hepatic microsomal enzymes causing enhanced metabolism and lowered anticoagulant response of oral anticoagulants (e.Merci deja